Editors’ pick: transcriptomes of 1000 genomes
نویسندگان
چکیده
منابع مشابه
Applications of the 1000 Genomes Project resources
The 1000 Genomes Project created a valuable, worldwide reference for human genetic variation. Common uses of the 1000 Genomes dataset include genotype imputation supporting Genome-wide Association Studies, mapping expression Quantitative Trait Loci, filtering non-pathogenic variants from exome, whole genome and cancer genome sequencing projects, and genetic analysis of population structure and ...
متن کاملHLA Diversity in the 1000 Genomes Dataset
The 1000 Genomes Project aims to provide a deep characterization of human genome sequence variation by sequencing at a level that should allow the genome-wide detection of most variants with frequencies as low as 1%. However, in the major histocompatibility complex (MHC), only the top 10 most frequent haplotypes are in the 1% frequency range whereas thousands of haplotypes are present at lower ...
متن کاملComprehensive analyses of genomes, transcriptomes and metabolites of neem tree
Neem (Azadirachta indica A. Juss) is one of the most versatile tropical evergreen tree species known in India since the Vedic period (1500 BC-600 BC). Neem tree is a rich source of limonoids, having a wide spectrum of activity against insect pests and microbial pathogens. Complex tetranortriterpenoids such as azadirachtin, salanin and nimbin are the major active principles isolated from neem se...
متن کاملParsimonious modeling of scaling laws in genomes and transcriptomes
We report here the use of Aevol, a software developed in our team to unravel the indirect selective pressures (i.e. pressures for robustness and/or evolvability) that act on the genome and transcriptome structures. Using Aevol, we have shown that these structures are under strong – although indirect – pressure due to the mutagenic effect of chromosomal rearrangements. Individuals undergoing hig...
متن کاملInference of Distant Genetic Relations in Humans Using “1000 Genomes”
Nucleotide sequence differences on the whole-genome scale have been computed for 1,092 people from 14 populations publicly available by the 1000 Genomes Project. Total number of differences in genetic variants between 96,464 human pairs has been calculated. The distributions of these differences for individuals within European, Asian, or African origin were characterized by narrow unimodal peak...
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ژورنال
عنوان ژورنال: Investigative Genetics
سال: 2013
ISSN: 2041-2223
DOI: 10.1186/2041-2223-4-17